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Home   COVID-19 treatment studies for Casirivimab/imdevimab  COVID-19 treatment studies for Casirivimab/i..  C19 studies: Casirivimab/i..  Casirivimab/i..   Select treatmentSelect treatmentTreatmentsTreatments
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Conv. Plasma (meta) Proxalutamide (meta)
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Ensovibep (meta) Remdesivir (meta)
Favipiravir (meta) Sotrovimab (meta)
Fluvoxamine (meta) Vitamin A (meta)
Hydroxychlor.. (meta) Vitamin C (meta)
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Other Treatments Global Adoption
Antiandrogens
Aspirin
Bamlanivimab
Bromhexine
Budesonide
Cannabidiol
Casirivimab/i..
Colchicine
Conv. Plasma
Curcumin
Ensovibep
Favipiravir
Fluvoxamine
Hydroxychlor..
Iota-carragee..
Ivermectin
Melatonin
Metformin
Molnupiravir
N-acetylcys..
Nigella Sativa
Nitazoxanide
Paxlovid
Povidone-Iod..
Probiotics
Proxalutamide
Quercetin
Remdesivir
Sotrovimab
Vitamin A
Vitamin C
Vitamin D
Zinc
Supplementary Data — Casirivimab/imdevimab for COVID-19: real-time meta analysis of 15 studies
Covid Analysis, January 22, 2022, DRAFT
https://c19regn.com/meta.html
0 0.25 0.5 0.75 1 1.25 1.5 1.75 2+ Regeneron (RCT) 38% 0.62 [0.30-1.28] recov. time 92 (n) 91 (n) Improvement, RR [CI] Treatment Control Regeneron (RCT) 54% 0.46 [0.20-1.08] recov. time 92 (n) 91 (n) Regeneron (RCT) 71% 0.29 [0.17-0.48] death/hosp. 18/1,355 62/1,341 Regeneron (RCT) 70% 0.30 [0.13-0.68] death/hosp. 7/736 24/748 Regeneron (RCT) 29% 0.71 [0.60-0.85] recov. time 1,355 (n) 1,341 (n) Regeneron (RCT) 29% 0.71 [0.60-0.85] recov. time 736 (n) 748 (n) Weinreich (RCT) 50% 0.50 [0.09-2.72] death 2/2,091 4/2,089 Weinreich (RCT) 67% 0.33 [0.03-3.17] death 1/1,355 3/1,341 Weinreich (RCT) -2% 1.02 [0.06-16.2] death 1/736 1/748 Weinreich (RCT) 71% 0.29 [0.17-0.48] death/hosp. 18/1,355 62/1,341 Weinreich (RCT) 70% 0.30 [0.13-0.68] death/hosp. 7/736 24/748 Weinreich (RCT) 29% 0.71 [0.58-0.87] recov. time 1,355 (n) 1,341 (n) Weinreich (RCT) 29% 0.71 [0.58-0.87] recov. time 736 (n) 748 (n) Webb 98% 0.02 [0.00-0.27] death 0/115 57/5,536 Webb 91% 0.09 [0.01-0.63] hosp. 1/115 538/5,536 Cooper 77% 0.23 [0.03-1.65] death 1/1,148 33/8,534 Cooper 48% 0.52 [0.23-1.20] ICU 6/1,148 85/8,534 Cooper 52% 0.48 [0.35-0.64] hosp. 45/1,148 703/8,534 Kakinoki 58% 0.42 [0.17-0.92] progression 13/55 22/53 Komagamine 77% 0.23 [0.01-4.63] ventilation 0/53 2/75 Komagamine 92% 0.08 [0.00-1.32] ICU 0/53 7/75 Komagamine 68% 0.32 [0.13-0.68] progression 8/53 33/75 Komagamine 29% 0.71 [0.58-0.87] hosp. time 53 (n) 75 (n) Suzuki (PSM) -200% 3.00 [0.12-73.3] death 1/222 0/222 Suzuki 60% 0.40 [0.05-3.45] death 1/314 5/635 Suzuki (PSM) 45% 0.55 [0.31-0.96] progression 17/222 31/222 Suzuki 50% 0.50 [0.31-0.80] progression 34/314 70/365 O'Brien (DB RCT) 85% 0.15 [0.01-2.78] hosp. 0/100 3/104 O'Brien (DB RCT) 92% 0.08 [0.00-1.37] hosp./ER 0/100 6/104 O'Brien (DB RCT) 33% 0.67 [0.43-0.98] symp. case 29/100 44/104 O'Brien (DB RCT) 40% 0.60 [0.45-0.81] viral load 100 (n) 104 (n) Horby (RCT) 6% 0.94 [0.86-1.03] death 944/4,839 1,026/4,946 Horby (RCT) 0% 1.00 [0.89-1.13] ventilation 479/4,556 487/4,642 Horby (RCT) 20% 0.80 [0.70-0.91] death 396/1,633 451/1,520 Horby (RCT) 12% 0.88 [0.73-1.06] ventilation 189/1,599 200/1,484 Somersan.. (DB RCT) 36% 0.64 [0.44-0.93] death 59/804 45/393 Somersan.. (DB RCT) 56% 0.44 [0.26-0.76] death 24/360 24/160 Somersan.. (DB RCT) 21% 0.79 [0.44-1.40] death 26/369 18/201 Somersan.. (DB RCT) 31% 0.69 [0.50-0.95] death/int. 82/804 58/393 Somersan.. (DB RCT) 29% 0.71 [0.53-0.96] no disch. 92/804 63/393 McCreary (PSM) 93% 0.07 [0.01-0.51] death 1/652 29/1,304 McCreary (PSM) 56% 0.44 [0.28-0.68] death/hosp. 22/652 101/1,304 McCreary (PSM) 48% 0.52 [0.33-0.82] hosp. 22/652 85/1,304 McCreary (PSM) 40% 0.60 [0.43-0.85] hosp./ER 40/652 133/1,304 Regeneron (RCT) 94% 0.06 [0.00-1.10] symp. case 0/186 8/223 Regeneron (RCT) 48% 0.52 [0.25-1.07] cases 10/186 23/223 Regeneron (DB RCT) 92% 0.08 [0.00-1.36] hosp. 0/841 6/842 Regeneron (DB RCT) 81% 0.19 [0.12-0.30] cases 20/841 108/842 Regeneron (DB RCT) 82% 0.18 [0.08-0.41] cases 7/841 38/842 Regeneron (DB RCT) 89% 0.11 [0.01-2.06] hosp./ER 0/753 4/752 Regeneron (DB RCT) 81% 0.19 [0.10-0.35] symp. case 11/753 59/752 Regeneron (DB RCT) 62% 0.38 [0.23-0.61] recov. time 753 (n) 752 (n) Regeneron (DB RCT) 69% 0.31 [0.17-0.55] viral time 753 (n) 752 (n) Isa (DB RCT) 93% 0.07 [0.01-0.28] symp. case 3/729 13/240 Isa (DB RCT) 93% 0.07 [0.01-0.28] cases 0/729 10/240 casirivimab/imdevimab COVID-19 outcomes c19regn.com Jan 22, 2022 Favors casiri/imdevimab Favors control
Figure S1. All outcomes.
Please send us corrections, updates, or comments. Vaccines and treatments are both valuable and complementary. All practical, effective, and safe means should be used. Elimination of COVID-19 is a race against viral evolution. No treatment, vaccine, or intervention is 100% available and effective for all current and future variants. Denying the efficacy of any method increases mortality, morbidity, collateral damage, and the risk of endemic status. We do not provide medical advice. Before taking any medication, consult a qualified physician who can provide personalized advice and details of risks and benefits based on your medical history and situation. WCH and FLCCC provide treatment protocols.
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